So for example, a certain virus can have an amino acid sequence that is very similar to the amino acid sequence of human cells. This can result not only in the production of antibodies against the virus, but can also lead to autoantibodies against the human cells due to the similarities in the proteins.
Epitope spreading. This is when the immune response to an infection causes damage to the self-tissues. An epitope is part of an antigen that is recognized by the antibodies of the immune system, and is what the antibody specifically binds to.
This is essentially a form of molecular mimicry. If there is a virus, normally the immune system will produce antibodies which attach to the epitope of the virus. Direct bystander activation. This describes an indirect or non-specific activation of autoimmune cells caused by the inflammatory environment present during infection.
Hopefully you now have a better understanding of how a virus can trigger an autoimmune condition. Epstein Barr. Epstein-barr virus EBV is one of the most common viruses in humans. EBV is usually spread through bodily fluids, primarily through the saliva 6. Although many people with EBV are asymptomatic, some of the symptoms associated with an EBV infection include fatigue, fever, sore throat, swollen lymph nodes in the neck, a rash, and an enlarged spleen 6. Some studies have also associated this condition with autoimmune thyroid conditions.
Another small study showed that EBV antibodies are more common in those with autoimmune thyroiditis 9. There is also evidence that EBV is linked to the development of various cancers, including nasopharyngeal carcinoma, gastric cancer, Burkitt lymphoma, non-Hodgkin lymphoma, and Hodgkin lymphoma It is also possible that EBV can increase the progression of thyroid papillary carcinoma to undifferentiated carcinoma Hepatitis C.
Hepatitis C virus is the most common chronic bloodborne infection in the United States Most people who become infected with this virus do so by sharing needles or other equipment to inject drugs, as well as the inadequate sterilization of medical equipment 13 Although sometimes the infection can be mild in some people, in others it can lead to liver cirrhosis, or even liver cancer.
There does seem to be a relationship between hepatitis C and thyroid health. This was confirmed in another study which showed that chronic hepatitis C infection can be associated with thyroid autoimmunity and hypothyroidism However, another study showed no significant association between chronic hepatitis C and thyroid autoimmunity, but it did show that interferon therapy for hepatitis C induced thyroid antibodies Parvovirus B Parvovirus B19 infects only humans, and the most common illness as a result of this virus is Fifth disease This is a mild rash illness, and some of the initial symptoms include fever, runny nose, and headaches It can also lead to rashes, along with painful or swollen joints.
I got my first dose of the Pfizer Covid vaccine on Tuesday, February 16th. I have Hashimotos although my thyroid was removed 2. Help with enlarged thyroid, rash and weight gain Mymallielu My daughter 21 has gained around pounds in less than a year. She has an enlarged thyroid, which you can see on her neck, she crav I'm really kind of new with all this, but I have Hashi's too and it seems to me that hashi's has an effect on almost everything that happens to my body.
Yeah, I know - my doctor tells me there is no relation too, but things in the neck area that would not have bothered me "pre-hashi" now just about knock my socks off. Helpful - 0. Thanks, Barb! Was wondering if it's just me or what! Next Question. Have an Answer? Notify me of new activity on this question. Join this community. You are reading content posted in the Thyroid Disorders Community Ask a question. Symptoms of an overactive thyroid are treated with a class of drugs called beta-blockers.
If the thyroid becomes underactive during the recovery phase, thyroid hormone replacement may be needed. The condition should improve on its own. But the illness may last for months. Long-term or severe complications do not often occur. The condition is not infectious. People cannot catch it from you. It is not inherited within families like some thyroid conditions.
Vaccines that prevent viral infections such as the flu may help prevent subacute thyroiditis. Other causes may not be preventable. De Quervain's thyroiditis; Subacute nonsuppurative thyroiditis; Giant cell thyroiditis; Subacute granulomatous thyroiditis; Hyperthyroidism - subacute thyroiditis. Guimaraes VC. Subacute and Riedel's thyroiditis. Endocrinology: Adult and Pediatric. Philadelphia, PA: Elsevier Saunders; chap Hollenberg A, Wiersinga WM. Hyperthyroid disorders. Williams Textbook of Endocrinology.
Philadelphia, PA: Elsevier; chap
0コメント